Louis Oosthuizen was born in Mossel Bay, South Africa. His early career was supported financially for three years by the foundation of fellow South African golfer Ernie Els.
He has won five professional tournaments on the Sunshine Tour:
- the 2004 Vodacom Origins of Golf Tour event at Arabella,
- the 2007 Dimension Data Pro-Am and
- Platinum Classic, and
- the Telkom PGA Championship twice, in 2007 and 2008.
He played on the European Challenge Tour in 2003 and has been a member of the European Tour ever since 2004.
In March 2010, he won his first European Tour event at the Open de Andalucia de Golf.
Louis entered the 2010 Open Championship at St Andrews ranked 54th in the Official World Golf Ranking, having made one cut in eight major championship appearances.
On the first day he shot a 65, placing him in second place, behind Rory McIlroy with 63, a 67 in the second round gave him a lead that he did not relinquish throughout the final two rounds. His two-day total of 132 tied the record for the lowest 36-hole score in an Open Championship at St Andrews. A 69 on Saturday placed Louis at 15-under-par, four shots clear of second-place Paul Casey. On Sunday Louis shot a 71 finishing with a 16-under par total of 272 for the championship, winning by seven strokes, the second lowest in St Andrews history.
Louis Oosthuizen became the fourth man from South Africa to win the British Open – following Bobby Locke, Gary Player, and Ernie Els – and moved to 15th in the Official World Golf Ranking.
- Louis finished the 2010 season in 10th place on the Race to Dubai also posting three further top-10s after his major win.
- In January 2011, he claimed his third European Tour title and a sixth here at home, winning the Africa Open in a playoff.
- In 2012, he successfully defended his title at the Africa Open.
- Louis was runner-up at the 2012 Masters Tournament. In the second event of the 2012 PGA Tour FedEx Cup Playoffs, the Deutsche Bank Championship, he finished second to Rory McIlroy.
On 10 September 2012, he reached the top 10 of the Official World Golf Ranking for the first time in his career. He finished the season ranked third on the Race to Dubai.
On 13 January 2013, he won the Volvo Golf Champions, shooting a six-under-par 66 final round to win the title by one stroke.
In January 2014, he retained the Volvo Golf Champions title by one shot over Branden Grace.
In June 2015 Louis was runner up placed 2nd in the US Open Championship and is now placed 16th on the Men’s World Golf ranking.